Growth Factor

A long-acting recombinant analog of Insulin-like Growth Factor 1, modified with an arginine substitution and 13-amino acid extension at the N-terminus to reduce IGF-binding protein affinity. Research has examined its role in cell proliferation, muscle protein synthesis, satellite cell activation, and anabolic signaling via IGF-1R. Extended half-life (20-30 hours vs 12-15 minutes for native IGF-1)…